Capitol Policeman John Cale has just been denied his dream job with the Secret Service of protecting President James Sawyer. Not wanting to let down his little girl with the news, he takes her on a tour of the White House, when the complex is overtaken by a heavily armed paramilitary group. Now, with the nation's government falling into chaos and time running out, it's up to Cale to save the president, his daughter, and the country.

The human government develops a cure for mutations, and Jean Gray becomes a darker uncontrollable persona called the Phoenix who allies with Magneto, causing escalation into an all-out battle for the X-Men.

While Batman deals with a deformed man calling himself the Penguin wreaking havoc across Gotham with the help of a cruel businessman, a female employee of the latter becomes the Catwoman with her own vendetta.