The series follows Carrie, Miranda, and Charlotte as they navigate the journey from the complicated reality of life and friendship in their 30s to the even more complicated reality of life and friendship in their 50s.

An outrageous cut-rate producer, Charlie LaRue (Christopher Meloni) is about to fulfill his lifelong dream to make a movie about the most offensive, dirtiest jokes ever told.

Carrie, Charlotte, and Miranda are all married now, but they're still up for a little fun in the sun. When Samantha gets the chance to visit one of the most extravagant vacation destinations on the planet and offers to bring them all along, they surmise that a women-only retreat may be the perfect excuse to eschew their responsibilities and remember what life was like before they decided to settle down.