One year after outwitting the FBI and winning the public’s adulation with their mind-bending spectacles, the Four Horsemen resurface only to find themselves face to face with a new enemy who enlists them to pull off their most dangerous heist yet.

Britt Reid (Seth Rogen), the heir to the largest newspaper fortune in Los Angeles, is a spoiled playboy who has been, thus far, happy to lead an aimless life. After his father (Tom Wilkinson) dies, Britt meets Kato (Jay Chou), a resourceful company employee. Realizing that they have the talent and resources to make something of their lives, Britt and Kato join forces as costumed crime-fighters to bring down the city's most-powerful criminal, Chudnofsky (Christoph Waltz).