A romantic getaway for two troubled college sweethearts turns into a struggle for survival when unexpected guests - and the surrounding environment - exhibit signs of a mysterious infection.

Capitol Policeman John Cale has just been denied his dream job with the Secret Service of protecting President James Sawyer. Not wanting to let down his little girl with the news, he takes her on a tour of the White House, when the complex is overtaken by a heavily armed paramilitary group. Now, with the nation's government falling into chaos and time running out, it's up to Cale to save the president, his daughter, and the country.