Seiya and the Knights of the Zodiac rise again to protect the reincarnation of the goddess Athena, but a dark prophecy hangs over them all.

X-Men, still grieving over the death of Phoenix (Jean Grey), are investigating a case of a missing mutant girl in Northern Japan. This leads them to a mysterious virus that turns mutants into monsters. U-Men and the Inner Circle want it.

Relaxing on a cozy beach, the Straw Hat Pirates are taking a rest from their quest. Right until Luffy noticed the Going Merry has been hijacked and sailed off from the beach. This leads them to search the ship and find the thief who took it from them. They ran into a duo named the Theif Brothers, who informed them that their ship was stolen by a group of pirates called the Trump Kyoudai. When they encountered the Trump Pirates, Nami ended up getting kidnapped as well as Luffy's hat. They tracked down the pirates to their base on Clockwork Island. Now Luffy, Zoro, Sanji, Usopp, and the Theif Brothers must reclaim the Going Merry, Save Nami, and get back Shank's straw hat.

Sakuragi Hanamichi is a junior high punk used to getting into fights and being rejected by girls but upon entering high school he meets the girl of his dreams, Haruko Akagi. He will do anything in order to win her heart including joining the school basketball team that is aiming to conquer the nation lead by Haruko's brother. The problem is that Sakuragi has never played basketball before and a freshman sensation is stealing the spotlight and Haruko's affection from him.